Combining medications can be dangerous, and Sudafed (pseudoephedrine) and codeine are no exception. Sudafed is a decongestant that helps relieve/clear/reduce congestion, while codeine is an opioid painkiller. Mixing these two drugs can lead to serious/potentially fatal/harmful side effects like respiratory depression/slow breathing/difficulty breat… Read More

Combining over-the-counter drugs like Sudafed with prescription opiates like codeine can be risky. Both work by affecting your central nervous system, and mixing them can lead to unpredictable side effects. These can include constipation, lightheadedness, and even overdose. It's crucial to always speak with your doctor before mixing any medications… Read More